Choose a tileset and get to mapping! Supported tiles will connect automatically to help you speed through the mapping process. Setting events on tiles is easy to do and populating your world with NPC’s and other items is easy to do.
Create things quickly with things like the character customizer or the experience curve editor. RPG Maker is made to let you change every single thing in your game swiftly and simply.
Everything you make is done through this powerful expansive database. You customize every character, weapon, enemy, and skill through this and so much more to make a designer's life easier.
Quickly script simple events with a few clicks. This powerful part of the editor allows you to get through the tedious amount of content for quests and other in game sequences quickly.
While a tileset in RPG Maker can encompass many files it also can be a hassle if you want to use multiple tilesets on a map. You can switch tilesets through code for multi-world game though.
RPG Maker was not really intended for multi-user support. There are a few tactics but for those of you who are used to with multi-user development may get annoyed.
There is a major stigma with using RPG Maker since it does have such a low bar to entry. If you do use this engine just make sure your game is so awesome that no one will care what it was made in.