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Pros
Pro Open source
Pro Powerful
Does not emulate, rather it translates Windows-specific system calls.
Pro Has many front-ends (kinda)
Like Play-on-Linux, Lutris, Winetricks.
Cons
Con Wine tends to favor some hardware over others
Tends to work better with nVidia graphics on an Intel CPU, even when an AMD CPU or graphics chip would normally perform better than the given equivalent part from Intel/nVidia.
Con Needs additional script sometimes
This can be done automatically by using PlayOnLinux.