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Pro Fits in perfectly with the GNOME desktop
Since it is a GNOME app, you get all the benefits of the GNOME desktop. It's easy to use, Epiphany just works out of the box. It stores your web site passwords in the secure GNOME keyring, and uses your existing desktop settings to launch applications and access the network, so you don't need to configure everything twice.
Epiphany is pretty lightweight and doesn't require much memory to start up.
Pro Default in many GNOME versions
Epiphany has been the default browsers for many distributions that use stock GNOME for a long time now (although it's being replaced by the much more popular Firefox lately).
Pro For Linux and Windows
Con Not much room for configuration
The choice for extensions is very limited, although there are decent extensions for the most useful activities and features it still cannot compare to the extensive collections that other browsers may have access to.
The number of tweaks that can be done to the browser from the options menu is also very limited since Epiphany follows a philosophy of "less is more". While this can be enjoyable for some it still hinders a lot of functionality and removes the ability to personalize the browser the way you want it to be.