Ranked in these QuestionsQuestion Ranking
Pro Integrates with read-it later apps
Integrates with Instapaper, Pocket and Readability.
Pro Integrates with a wide variety of RSS services
Reeder supports Feedbin, Feedly, Feed Wrangler, Fever, FeedHQ, Inoreader, NewsBlur, Minimal Reader, The Old Reader and BazQux Reader.
Pro Integrates with Instapaper
Pro Nice keyboard shortcuts
You can also customise keyboard shortcuts.
Con Can't remove unused tags
Once you create a tag, it will always show up in tag selection screen. There's no way to delete it from the list.
Con Can't edit tags
If you've made a typo, you have to create a new tag. You can't rename the existing one.