Ranked in these QuestionsQuestion Ranking
Pro There are versions for a lot of applications or it's easy to make your own
There are ready-made packages for Vim, IntelliJ, Emacs, iTerm, etc. If your app isn't supported the website explains clearly what colors are used, so it should be easy to wrap up your own.
Pro It seems that is has been given the most thought
Judging from the description that has been given by the author, it seems that this color scheme has been designed with huge background knowledge about colors and relations between them.
Pro Works well with multiple fonts
Since Solarized has pretty good color separation it's easier to distinguish both thin and bold fonts.
Con Too much blue
People caring about the color intensity in their screens, will notice that this theme is not useful for night use. If you use software like Flux to dim the blues in your screen this theme loses its enchant.
Con Vanilla version doesn't work with htop
Half of the usernames in htop have the same color as the background.
One has to use a patched version of htop.
Con Low contrast
Comments for example, have very low contrast against the background which makes it harder to read.