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Pros
Pro Fast storage solution
There is an M.2 port on this board which allows one to use a M.2 SSD for storage. These SSDs allow for faster read and write times over a SATA SSD (can be over 50% faster), which translates to faster boot and loading of games.
Pro Good multi-graphics options
This board is able to use 3 way and 2 way Crossfire as well as 2 way SLI. It has 2 PCI-Express 3.0 x16 slots (one runs at x8), 1x PCI-Express 2.0 x16 slot (runs at x4), 3x PCI-Express 2.0 x1 slots as well as 1x PCI slot. This gives many options not only for PCIe devices but GPUs in particular.
Cons
Con No power button on the board
Many high end boards include a power button on the board in order to test it before assembling the whole PC in its case. That is not an option here, which can cause issue if something is faulty as everything will have to be torn down to return it.
Con Hard to access SATA connectors
When using the 16x speed PCIe port for an installed graphics card, the graphics card will cover some of the SATA ports. While they are not unusable, they will need to be plugged in before the graphics card is installed. They will also be inaccessible after that point unless the GPU is taken out.