Microsoft's Surface Studio is their first in-house built desktop, following their Surface line of tablets. Nearly all of the components are housed in the base, and the entire display tilts down to 20 degrees.
Note: this isn't available yet. Pre-orders ship early November, - more information to come
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Pros
Pro Amazing accessories
The Surface Pen (included) is back with the Studio, but a new addition is the Surface Dial (sold separately for $99). This dial provides haptic feedback, and can rotate. It has a grippy rubber base, which means you can place it on the screen and it will stay there. Rotating it can do different things - rotate the image on the screen, change colors of the pen while drawing a continuous line, or rotate images in a 3D space (which Microsoft is pushing in their next update in early 2017).
The Surface Pen works similar to previous versions - it can measure pressure sensitivity, and there are buttons on the side that allow for selection or other functions.
Pro Large, versatile, amazing display
The 28" display has an interesting aspect ratio of 3:2, and it has an extremely high resolution of 4500x3000 (slightly more than 4K). It also has different modes (built into the software) to display Adobe sRGB or Vivid Color Profiles. This allows content creators to both see the true colors, but also how they will likely be displayed on an average display. This display has a pixel density of 192ppi, which allows you to get very close to it without being able to see individual pixels.
The screen is also a touchscreen, with sensors for both the Surface Dial as well as the Surface Pen. In addition to all of this, they are marketing it as the thinnest display on any AIO (all in one) desktop which is technically true - it is the thinnest, however most of the internals are housed in the base.
Cons
Con Extremely expensive for the internal hardware
For $3000 starting price you'd expect to get the bleeding edge of performance. But you don't. The internal graphics is either a nVidia GeForce GTX 965M (2GB) or the 980M (4GB), which are mobile graphics from last generation. There is no USB type C or Thunderbolt connections. The base model also starts at an i5 (the specs page doesn't list the specific version) processor.