Ranked in these QuestionsQuestion Ranking
Pro Native experience and clean user interface
Postico is a native OS X app which is available through Mac App Store. The UI is fast, responsive and integrates seamlessly with the OS.
Pro Created by an experienced developer in the field
Postico is the successor of PG Commander, an older Mac Posgres GUI tool which is also widely used. They are both maintained by the same person.
Con No multiple query tabs
To be fair, multiple windows / tabs IS a feature. It's just part of the paid version.
Postico is a commercial app, with a one-time fee of $35. There is a a free trial available