Pro Virtually no protocol or traffic restrictions
Except for SMTP port 25 currently being filtered, you can use any and all protocols at your disposal, no traffic is restricted.
Pro PayPal and CC payments
Pro Basically no logs are kept
Con Has officially shut down their service
Privacy.io has stopped functioning as a business as of June 18, 2014.
Con SMTP port 25 is filtered
Though it's only to mitigate spam and they are working towards a better solution.