Ranked in these QuestionsQuestion Ranking
Pro Provides a native experience
Through using Titanium's API and UI components similar to that of the platform's native UI, Titanium provides a native experience.
Con Has specific requirements with regards to installed libraries
Prices start at $39/month for an indie subscription. For a team account, the price is $249/month per seat.
Con Most plugins are paid
Appcelerator Marketplace is meant to sell to developers 3rd party plugins and functionalities as well as code samples. Thus, people will prefer to sell you their plugins and samples instead of making them open source. This will increase costs of development.
Con Lack of capabilities
For example, there is no way to read QR codes natively.