Ranked in these QuestionsQuestion Ranking
Pro Quick and easy keyframe animation
Animation is calculated as movement paths between keyframes, and creating a keyframe requires only placing sprites and assigning a time index.
Pro Easy configuration of character maps
Spriter makes it easy to change the character skin, and the animations persists.
Pro Free upgrade to Spriter Pro 2
Free upgrade to Spriter Pro 2.
Price is a lot less than Spine for the pro version and goes on sales often.
Pro Steam intergration
Steam integration is great for updates and tracking hour progression with the software.
Con Sluggish performance with Unity Runtime
Con This version will never have 3D mess support
Yes, there will be a free upgrade to Spriter Pro 2 which will have this feature, but it will be years until that program is read as mentioned on the official site. The issue being that they do not have a way to program this in their current exported runtime. So, for not both Dragon Bones, Spine, and Blender, are the best options it seems for 3D mesh support which really adds something to game animations.
Con No curved paths
All motion paths are linear. Curves have to be simulated by hand-placing additional keyframes.
Con No hotkeys for stepping through animation frames
Stepping the animation forward and backward requires using the mouse, extremely inconvenient when fine-tuning motion paths.
Need knowledge in animator specification of profession