Made with Unity as a tool to quickly create tilesets based on a few textures. This tool also allows for automatic tiling within Unity to quickly create tilemaps.
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Pros
Pro Free tile-placement plugin
AutoTileSet is a tile placing tool part of the AutoTileGen family that is supported in Unity, Construct 2, and GameMaker to create tilemaps. AutoTileSet does not need AutoTileGen to work.
Pro Auto-creates tilesheets
Auto Gen Tile takes a few image parameters and a few settings that will quickly create a full tilesheet with 48 tiles for full bordered terrains.
Pro Auto-creates borders on tilemap
While placing tiles on the tilemap AutoTileSet will place appropriate borders and filler tiles instead of the user having to change each tile for each variation. It also support multiple tile sheets for variation and placing them correctly.
Cons
Con Extra work needed for Isometric Tiles
Isometric tiles are not technically supported but can be achieved with camera work and setting up tile art yourself.