R model has a self-cancelling AA filter.
Max video resolution: 1080p30
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Pro Flicker detection
The camera can detect flickering light sources and sync up with them to shoot at peak brightness in order to avoid underexposing the image by accident.
Pro Good autofocus system
61-point autofocus system with 41 cross-type points that performs well in low light. In addition, 5 central autofocus points turn into dual-cross-type points with fast (f/2.8 or faster) lenses increasing the precision even further.
Pro Natural skintones
Pro Excellent build quality
The 5DS/R has a magnesium alloy shell that makes it durable.
Pro Programmable Auto ISO
Pro In-camera timelapse
Pro High resolution
50.6 MP compared to 22.3 MP for the 5D Mark III.
Con Limited video capabilities
No HDMI output, no headphone socket.
Con Dynamic range could be better
According to tests performed by DxOmark 5DS / R has 12.41 stops of dynamic range in print and 11.08 stops on screen for images taken at 100 ISO while cameras in this price range commonly push 14 in print and 13 on screen.
Con AF subject tracking could be better
Con Low max ISO
The cameras go up to 6400 (or 12800 in extended) ISO.