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10 Options
Moqups is a nifty HTML5 App used to create wireframes, mockups or UI concepts, prototypes depending on how you like to call them.
SpecsUpdate
PlatformsWeb
Pros
Know any positive aspects of this option?
Cons
Con Doesn't support Internet Explorer
Not a problem for iOS projects but it can hinder Windows-centric ones.
Know any negative aspects of this option?