Recs.
Updated
SpecsUpdate
Pros
Pro Allows different wallpapers/screensavers for each monitor
While Windows limits your customization to 1 wallpaper and 1 screensaver, which has limitations for certain applications. For example, if your monitors have different resolutions or aspect ratios, wallpapers don't always play nice. Display Fusion lets you have a different wallpaper for each monitor which alleviates issues like this.
In industrial applications, this means that you could have a customer-facing monitor which has a different (more professional) wallpaper and screensaver.
Pro Shortcuts for window management
Using keyboard shortcuts, you can lock your mouse to the confines of an area (a window, or even a specific monitor - useful for gaming), as well as resizing or moving the window. These are great additions to the window shortcuts built into Windows (alt+tab, Alt+F4, Win + D, etc).
Cons
Con Window splitting configuration requires manual input
The GUI for window splitting can be a bit tedious to work with - while it offers great customizability, it does require either calculating how many pixels you'd like, or trying it hit-and-miss if you'd like to i.e. fit an IM program with the contact list to a side of the screen. In other words - no real-time preview, and the splits' edges don't travel together when adjusting edges around.