Sketch is a popular tool for web and app design. It has the best features from Photoshop and Illustrator packed into one without the fluff.
Pro Vector based yet pixel aware
You can rescale assets without quality loss, easily export x2 assets for retina designs and design high quality icons & artwork. Being pixel aware lets you set a grid and snap objects to it as well as round to the nearest pixel edge to clean up your layers.
Con License based payment model
Sketch has recently decided to cease development of major version (2.0, 3.0, 4.0) with free updates in between, and has switched to a license based subscription model. A yearly license costs $99 and includes the latest version of the Sketch software, plus a year of free updates. After this license expires, you can renew for another year of updates - or continue to use the current software without updates.