Django is used in many high-visibility environments (evidenced by the who uses django section on the homepage), and has a substantial history. Embraces commonly-used MVC pattern,...
Ruby on Rails
Ruby on Rails is a widely used open source web framework written in Ruby. It's a MVC framework which emphasizes the use of many well-known software engineering paradigms, such
Play is a Scala based web framework that eschews traditional Java web-development practices and embraces a more modern approach, analogous to the Rails or Django.
Express is a minimal and flexible node.js web application framework, providing a robust set of features for building single and multi-page, and hybrid web applications.
Symfony is a free PHP web application framework for MVC applications.
Hapi is a rich web application server framework for Node.js.
Dropwizard is a Java framework for developing ops-friendly, high-performance, RESTful web services. Dropwizard pulls together stable, mature libraries from the Java ecosystem in...
Catalyst - Perl MVC framework