Ports for Atom, Sublime, TextMate and Emacs and other text editors are available.
For a full list of available ports: https://github.com/morhetz/gruvbox-contrib
If you are using a Jetbrains IDE: https://github.com/morhetz/gruvbox-contrib
Size of the tabs, icons of file types, contrast of the color schemes, accented colors, indentation in the sidebar, sizes of the status bar and dozens more.
Without being fully black on white (which is good on modern already very contrasted screens) it remains pretty dark compared to many alternatives; making it more readable.
People caring about the color intensity in their screens, will notice that this theme is not useful for night use. If you use software like Flux to dim the blues in your screen this theme loses its enchant.
There are ready-made packages for Vim, IntelliJ, Emacs, iTerm, etc. If your app isn't supported the website explains clearly what colors are used, so it should be easy to wrap up your own.
Judging from the description that has been given by the author, it seems that this color scheme has been designed with huge background knowledge about colors and relations between them.
Base16 template repositories on github have configurations for most popular applications where a color scheme can be applied. This reduces headache for users when applying or switching color schemes.
You may not be able to use as many colors as you want for a particular application without manual manipulation since base 16 color schemes are limited to 16 colors.
The base16 color schemes are really great but as a vim theme they require a lot of manual tweaking to be viable. One example is that in one theme a neon green bg is used with a white fd rendering any part of the vim UI that uses those two colors together illegible.
This is just one example of an app that doesn't work with vanilla Solarized Dark (half of the usernames in htop have the same color as the background)
One has to use a patched htop version.
Despite being primarily beige and green toned, the color scheme makes use of warm colors for some syntax highlighting groups, which can outshine the "calm" feeling in certain languages.