SuperDuper is with you every step of the way. It explains the process from preparation to successful copy. This is convenient for new users who are not familiar with the app.
The interface is extremely streamlined. It walks you through the entire process. There are advanced options but they remain hidden until you want them.
Get Backup Pro doesn't give an option to select the internal drive as a destination for cloning content from folders.
Edit: Nevermind, the sync function is the proper way to achieve this. Flagging this. +1 for slightly unintuitive workflow.