Controls in the BIOS can be accessed through a desktop GUI app, meaning the user does not need to boot into the BIOS in order to change their settings. This is great for fan controls as well as other key settings.
Depending on how high the heatsinks are on ones RAM modules, it may be too close to the CPU when using a tower cooler. Depending on ones case size and how they have to attach the cooler, the RAM may get in the way.
The GPU will cover some of the SATA ports making them inaccessible if a GPU is used. That means the GPU will have to be taken out in order to gain access to those ports, either to add a new drive or unhook one already plugged in.
While the onboard sound is serviceable, a dedicated card will sound much better. This can often be the norm for a motherboard, but there are boards out there wil quality built in sound, this is just not one of them.
The board uses high quality audio capacitors as well as has a separated zone on the board to protect it from electrical magnetic feedback. This way it can provide clear audio with no feedback from the power that is constantly going through the board.
The board is made with specially woven glass fabric that eliminates large gaps in the material. This helps with humidity protection, which is great for those that live in a humid region or use a humidifier in that particular room.
While the board may look black in color in pictures, up close you can see that it is actually brown. While not a huge issue, those that do like to match their color schemes of components may have a hard time finding anything that really goes with this brown color.