A game where Isaac is trying to escape his mother from killing him because she heard a voice from God. The game is a top down view and is played by using just the keyboard.
Pro One of a kind
One of the best roguelikes out there. Difficult to beat completely and oh so very satisfying. Gazillions of unlocks, secrets, bosses, power-ups and item combinations. Limited co-op (BoIR only). The game can be genuinely terrifying and dark, especially if you take a moment to ponder what's really going on with its backstory and characters.
Pro Incredible amount of content
The Binding of Isaac: Rebirth has all of the original games content as well as many new add ons such as the Wrath of the Lamb expansion as well as many extra characters.
Lots of characters each with their own unique starting abilities, plus many challenges gives the game really high replay value.
Pro Powerups combine in very unique ways
There are tons of unique power ups, and most of them interact with each other to create really interesting combinations. The main attack in the game is shooting a projectile, and modifiers on top of that stack making for really interesting attacks. For example, you can have a homing, multi, laser attack that shoots in both directions by combining multiple treasures. You can build really interesting strategies this way and that keeps the game feeling fresh.