When comparing Moai SDK vs Oxygine, the Slant community recommends Oxygine for most people. In the question“What are the best 2D game engines?” Oxygine is ranked 18th while Moai SDK is ranked 19th. The most important reason people chose Oxygine is:
Most interesting is ability to build C++ Oxygine application for Web via Emscripten. So you write C++ code and it will compile it to HTML5/JS.
Specs
Ranked in these QuestionsQuestion Ranking
Pros
Pro Fast
Because it uses Lua + C++.
Pro Gives you total control
You can use your own custom shaders and extend the language with C++. MOAI doesn't give you everything, instead it gives you the tools you need to develop any game you want.
Pro Full source code is available
So it is extendable with C++
Pro Easy-to-use particle engine
Uses a limited subset of Lua
Pro Uses Lua, with LuaJIT where possible

Pro Is used by many pro developers
Moai SDK is used by popular developers including Double Fine for their mobile game, Middle Manager of Justice, and for their Kickstarter hit, Broken Age(formerly, Double Fine Adventure.) It was also used to create the popular mobile game Bubble Ball 2.
This proves that this engine can be used to make fully-featured and fun games.

Pro API interfaces
Has options for development like Hanappe and Rapanui, providing a different way to interact with the engine.
Pro Helpful community
The Moai SDK Forum is active and users will go to great extents to answer queries, post code snippets, beta test, and even purchase and give feedback on each others' games.
Pro Helpful and detailed documentation
Although the Moai SDK is very advanced and uses complicated features, the documentation wiki thoroughly and clearly explains how to use these features, such as the Moai Cloud(a service that provides web services for your game), and multiple ways to build from source.
Pro Games can be built as HTML5 applications
Most interesting is ability to build C++ Oxygine application for Web via Emscripten. So you write C++ code and it will compile it to HTML5/JS.
Pro Functionality can be extended with a bunch of available extenions
All of them available publicly at github.
- oxygine-movie for playing Theora movies with alpha channel
- oxygine-sound player for ogg sound/music with streaming
- oxygine-freetype library
- oxygine-billing for in-app-purchases on Android/iOS
- oxygine-spine for playing Spine animations
- oxygine-magicparticles for playing particles made with MagicParticles
Pro Will be familiar to users of ActionScript3/Flash API
If you are familiar with ActionScript3/Flash API, then you will find it easy to begin working in Oxygine. Oxygine is much like Flash in C++, as its Event Handling model is very close to that of ActionScript 3 and SceneGraph.
Pro Easy to use C++ API with optional C++11 features
Oxygine is written in C++. It provides easy to use API, which is designed with "do more with less code" philosophy. It uses a managed scenegraph system that takes care of rendering and updates, and provides ability to extend with custom rendering and updates.
Pro Free, open source and cross-platform
Oxygine is a free framework that works on OS X, Windows, Linux, iOS, Android, HTML5. It's licensed under MIT with source code available on GitHub.
Pro Robust
It's very rare to experience bugs with Oxygine.
Pro Allows playing movies with alpha channel
Using oxygine-movie extension for Oxygine you could play in your game any videos encoded with Theora codec.
You movie could have alpha channel and used as simple sprite instead of classic spreadsheet animations.
Pro Allows for flexible contol over draw processes
Pro Fast
Cons
Con Not for beginning developers
The Moai SDK has very advanced features which allow it to create powerful games. A drawback from this is that it is not very suitable for beginners.
Con Not necessarily tested or stable

Con Scarce documentation
Since it is a minimalist framework there is not that much documentation, but if you are used to reading API references and source code you are good to go!
Con Development has ceased
The last update was over a year ago. Users should not expect things to still work on future OS versions unless they're ready to fix them yourself.
Con Inactive
The project does not seem to be active: there has been no new commit since mid-2019, the Twitter feed for the engine stopped posting news in 2018, and the forum is offline as of May 2021.
Con Little community support
Oxygine is a young framework. It was first released in 2013 and has yet to gather a large community. As of February 2016, the forum had just 123 members.
Con Not many tutorials available
There are not many tutorials available that teach developers on how to make a game with Oxygine from scratch. Because of this, it may be harder to pick it up or to start learning game development by using this engine.
