When comparing pygame vs PureBasic, the Slant community recommends pygame for most people. In the question“What are the best 2D game engines?” pygame is ranked 16th while PureBasic is ranked 40th. The most important reason people chose pygame is:
Pygame uses Python as its scripting language. Python is widely considered one of the easiest languages to grasp even for beginners.
Specs
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Pros

Pro Easy Python syntax
Pygame uses Python as its scripting language. Python is widely considered one of the easiest languages to grasp even for beginners.
Pro Very easy to understand
The API is very straightforward.
Pro Good canvas system
Pygame has a drawing system that allows the user to create and draw on an unlimited number of canvases.
Pro Standalone executables
Can create single file executables without the need to install other libraries, run time environments, etc.
Pro The syntax is very beginner-friendly
Pro Same code on Windows, OS X and Linux
Same code can be compiled natively, without any interpreter for OS X, Windows or Linux, using the native GUI toolkit of the OS
Pro Many integrated features
Many libraries available without additional installations : 2D & 3D, database, network, sound, xml, JSON, http...
Pro Allows to program at a lower level than most alternatives
Pro Lifetime license
Pay once, use forever.
Pro Constantly updated
Pro Supports ARM in addition to x86, AMD64 and others
Pro Can compile to plain C code
Pro Grest user community / forums with the developer very active
Cons

Con Deathly slow
Con Nonexistent community
No good forums, wiki, or other ways to reach other Pygame developers.
Con Very basic
Pretty much just a wrapper for SDL.
Con Pygame is a multimedia framework, not a game engine
Physics, AI and networking are not supported.
Con Messy documentation
The docs are messy, and some basic functions are infuriating to work out. There's even some places in the documentation where it's clearly wrong about how a method is called/what the arguments really do.
Con Outdated
Pygame uses a really old version of SDL and is missing some of the features developed for SDL2.
Con Hasn't been updated in years
Hasn't been updated in years.
Con Limited free version
Free version is limited to 800 lines and can not create DLL's.
Con Some bugs are present on the Linux platform
Con Slightly bogged syntax
Sometimes the syntax bogs down, just a little with long procedure names and such. A truly minor issue.
Con Not RAD
Not a RAD environment.
