When comparing Microsoft XNA Game Studio vs Nez, the Slant community recommends Microsoft XNA Game Studio for most people. In the question“What are the best 2D game engines?” Microsoft XNA Game Studio is ranked 80th while Nez is ranked 89th. The most important reason people chose Microsoft XNA Game Studio is:
it is very easy to import your own 2 dimensional assets
Specs
Ranked in these QuestionsQuestion Ranking
Pros

Pro Easy assets
it is very easy to import your own 2 dimensional assets

Pro Very easy to use
relies largely on drag and drop elements and has been used to create notable high quality 2d games such as DLC Quest
Pro Active community
The community is very active, so if you ask for help you'll get it relatively quickly.
Pro Open source
Completely free, no need to pay for licenses.
Pro Cross-platform development thanks to the use of mono and xamarin
Nez is built on top of monoGame and can be used the make games for many platforms (Windows, Linux, Mac, Android or IOS).
Cons

Con It's dead
It is not getting updated and Microsoft does not recommend using it anymore.

Con Limited platform support
Only supports Xbox 360, Windows and Windows Phone
Con Just a framework
Meaning there's no visual scene designer so you'll have to write your own.
