When comparing Pure CSS from Yahoo! vs mini.css, the Slant community recommends mini.css for most people. In the question“What is the best CSS framework?” mini.css is ranked 4th while Pure CSS from Yahoo! is ranked 15th. The most important reason people chose mini.css is:
The whole framework is built on flexbox and works really well on most platforms.
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Pros
Pro Easy to customize
Has an extremely minimalist look that is super-easy to customize since it basically gives designers just a foundation on which they can easily build their design.
Pro Cross-Browser compatibility
A solid base built on Normalize.css to fix cross-browser compatibility issues.
Pro Lightweight
Extremely small file size: 4.5KB minified + gzip.
Pro Responsive
A responsive grid that can be customized to your needs.
Pro Works well with Bootstrap
Easily use Bootstrap CSS and JS elements within the framework.
Pro Flexbox-based
The whole framework is built on flexbox and works really well on most platforms.
Pro Active developer
The developer is actively maintaining the project and responding to any issues and questions.
Pro Minimal
The framework is really tiny, under 7KB gzipped.
This is what makes mini.css stand out, because it looks like a pretty powerful library and it still is under 10KB.
Pro Responsive
It works great on all devices, mobile websites are really easy to develop and view.
Pro Style-agnostic
Few flavours so far, but there is a lot of space for customization.
Pro Great documentation
From basic syntax, templates, examples, customization to-dos and don'ts. The documentation is pretty great.
Pro Supports CSS custom properties (var)
No other framework supports CSS variables right now (as of November 2017). The latest alpha of mini.css supports this feature, making customization even easier.
Pro Accessible
ARIA rules are a priority and it works very well for all users.
Works really well with screenreaders.
Cons
Con Not suitable for beginners
Since Pure CSS only carries a minimum number of styles out of the box, it might not be great for beginners who want a complete style that looks good out of the box without having to customize it.
Con Archived
Git repo has been archived so it's pretty unlikely to receive bug fixes or new features.
Con Not widely used
A large community is always an advantage especially for open source projects. It means better documentation, continued development, and lowers the possibility for the project to be abandoned in the future since the probability for someone from the community to keep maintaining it is larger if the community is larger.
Con Single developer
There is no team developing this framework, except one guy.