When comparing RPGMaker vs Blender, the Slant community recommends RPGMaker for most people. In the question“What are the best game engines for beginners and non-programmers?” RPGMaker is ranked 7th while Blender is ranked 10th. The most important reason people chose RPGMaker is:
It's possible to create a game with absolutely no art or coding skills, so even complete beginners can make something.
Specs
Ranked in these QuestionsQuestion Ranking
Pros
Pro Easy to jump into using an intuitive WYSIWYG editor
It's possible to create a game with absolutely no art or coding skills, so even complete beginners can make something.
Pro Large and active community
The engine has seen multiple iterations since 1995, so a large online community exists that is always willing to help each other out.
Pro Ruby / Javascript support provides depth to more experienced developers
With a script editor that uses a modified version of Ruby, it's possible to go well beyond the traditional RPG with this engine. Note: XP and VX use Ruby, the latest version "MV" uses Javascript for scripting.
Pro It's an open engine
It's possible to use custom editors from the community, edit libraries,include libraries,etc (MV Only)
Pro Multi-platform
MV supports HTML5 exports, so it is easier than ever to make your game work on iOS, android, OSX,Linux or Windows.
Pro Inbuilt database and multplayer plugins, providing you the scalfolding to customising your projects with ease
The inbuilt database which binds to game saves or can be made persist allows great power within your logic. Also a plugin called 'Alpha.net' provides multiplayer. This combination can allow great customisation of the engine, allowing a powerful 2D game to be made with little to no coding experience.
Pro Greater Map layers
MV Mapping uses an additional layer to create better depth.
Pro MV has HTML5 export
You can now HTML5 export your projects, so you could theoretically host your game on your webserver, and have your friends play the game without ever having to install a single thing.
Pro A cheap license that allows using the software commercially
There are several versions of RPG maker, with MV being the latest and most fully featured: MV ($79.99), VX Ace ($69.99), VX ($59.99) and XP ($24.99), 2003 ($19.99).


Pro Free and open source
Blender is licensed under the GPL. Some Blender modules such as the Cycles rendering engine are licensed under the Apache 2.0 license.

Pro Wide import and export format support
Support lots of modern 3D formats including DAE and FBX - ideal for game developers.
Pro Has a powerful rendering engine
Blender runs the Cycles path tracing engine under the hood. Cycles is a very powerful rendering engine capable of full path tracing (light fall off, caustics, volumetrics). It is mostly compatible with OpenCL and CUDA rendering, and is implementing mycropolygon displacement features. The upcoming release has a viewport engine called EEVEE whereby you can see and interact with your work in render mode in real time!

Pro Python extensibility
Blender embeds Python 3, which can be used to write add-ons, tools, extend the interface, rig characters and automate tasks.

Pro Powerful animation suite
Blender provides a full rigging system, and automates animation by interpolating between keyframe positions.
Pro Supports both low-poly and hi-poly modeling

Pro Regular release schedule
Releases are made every ~3 months.
Pro Sculpting and 3D painting features
Although Blender's 3d painting and sculpting tools (mostly painting) are not at par with specialized software like Substance Painter, ZBrush, or Mari, it is more than capable of getting most jobs done if the user takes the time to learn and understand it.

Pro Includes video editing & compositing tools
Blender's node-based compositor has comprehensive video sequencing and post-processing features.
Pro Node based modeling support
Pro Keyboard shortcuts
Good keyboard shortcuts for everything. Keep your left hand on the keyboard and your right hand on the mouse.
Pro Very useful for a freelancer
It offers a round solution (it covers many areas and professional fields) for a freelancer, for free, constantly updated, very polished, and allowing high quality results that clients do require. After some learning, it becomes very useful for professional work.
Pro Has a large community
There's a huge community to help you get started immediately.
Pro Coherent and streamlined workflow / internal use logic
The trick with Blender is to get used to its usage philosophy, as it keeps consistent through all the application. Once you get it, every feature or addition is learnt naturally, almost effortlessly.
Pro Very versatile
You don't have to switch between software when you want to do different things. Because modeling, sculpting, composting, video editing etc can all be done in blender.
Pro Generative geometry using nodes
Cons
Con You have to code when you want something didn't built in
You know,RM series' default walk animation only has three frames.If you want to enhance,you have to code by yourself——especially majority of it's user are newbies.
Con No Hardware accelerate
You'll get a bad performance when you have big animations,especially in MV,which can easily change into higher resolution.
Con No 3D support
None of them have 3D support, it is possible only with manual scripting which could be difficult for beginners.
Con MV Does not have a "REAL" Android export.
MV has an export to HTML5 - which can run on any browser including android. It is however not a "native" app export.
Con Inconsistent included visual assets
Included visual assets within MV have inconsistent presentation. Though RPMMV does contain enough to make a small basic title, the visual assets don't often look like they should be mixed on-screen.
Con No built-in realtime battle system
RPG Maker series has only turn based battle systems, unless scripts/Plugins made by the community are used.
Con Conversion to MV difficult
Older iterations of RPG Maker use smaller sprite sizes that require manual conversion to use older RTP assets and older assets are more robust.
Con Too many possibilities, no unified workflow
The operations are not optimized enough for specific tasks.
Con The physics engine is a bit lagging behind, especially the destruction physics
Con Difficult learning curve
Blender has a history of being unintuitive, but the 2.8 overhaul made the program far easier for beginners to pick up, and changes continue to be made to further improve the experience. However, there is still a learning curve.
Con Not good for Industrial Design because it uses average vertex normals
You can not create a hard surface with a radius continuity degree along a surface using a specific radius value.
Con Vertex normal issues on edges after boolean operations.
After creating a simple boolean operation the vertex normals are broken. A lot of work to fix the issue and you loos surface continuity.
Con Bad vertex normal after boolean operations
Does not handle well polygon intersections. And need tweaking by hand points or adding average vertex normals via modifiers.
Con Does not handle NURBs
Is not capable of real hard surface for industrial design because is not able to reproduce surface continuity degree as a NURBs does and average vertex normal destroy surface radius.
Con Poor particle system
The Blender particle system can at times be a little limiting and finicky (and buggy) to get working. Even if it can get most straight forward jobs done, it is far from the most advanced system, and could benefit largely from advancements.
