When comparing Genome2D vs Blacksmith 2D, the Slant community recommends Genome2D for most people. In the question“What are the best 2D game engines?” Genome2D is ranked 47th while Blacksmith 2D is ranked 48th. The most important reason people chose Genome2D is:
It's the fastest gpu-based framework out there for flash. It's beautifully optimised. It has very low rendering latency, low level OpenGL calls that other tech simply cannot do (ie Unity) due to Stage3D, and thus can render a lot more data quicker
Specs
Ranked in these QuestionsQuestion Ranking
Pros

Pro Lightning fast
It's the fastest gpu-based framework out there for flash. It's beautifully optimised. It has very low rendering latency, low level OpenGL calls that other tech simply cannot do (ie Unity) due to Stage3D, and thus can render a lot more data quicker
Pro Cross-platform mobile, desktop and web
Supports Windows, Mac OS X, Linux, iOS, Android, Web and native Flash.
And with the HTML5 export, it also potentially supports development for the Wii U :)
Pro Haxe!
Haxe is a strictly typed programming language that saves development time but still compiles high performance executables, and can build for tons of different platforms (flash, c++, html5, java, c#, etc.)
Pro Access to direct draw features
Has access to direct draw features so you can make you own rendering structures (scene graphs etc).
Pro Automatic dynamic batching
Automatically batch geometries with dynamic batching techniques (by using constant buffers).
Pro Component based architecture
Pro Cache as bitmap
Automatically detects changes and updates bitmap cache. Allows to gain even more performance on heavy scenes and runs smoothly on old devices.
Pro Most valuable when size matters
All engine code is written in ES6, fully GCC typed, allowing to eliminate all dead code from your app.
Pro Advanced scene graph and rendering pipeline
Dirty flag tracks scene changes and avoids unnecessary calculations and context calls. If no changes were made to the scene since last frame, no rendering will be done. Battery efficient.
Pro Good performance
According to the tests on the Github page, the performance is better than in Phaser!
Pro Good and clear source code
The source code is well commented and easy to understand.
Pro Super small build size
Super small build size through dead code elimination. The best for playable ads and Facebook Instant Games.
Cons
Con Lacks documentation
The API documentation is minimal, there's not many tutorials and the ones that are there are very small and only cover the basics. If you want to learn how to properly use it, you have to ask the community or read the source code and figure it out.
Con Not too many games to showcase it
Con Slow development rate
Con Small community
The project is young, so the community is extremely small.
