When comparing WiMi5 vs Ren'Py, the Slant community recommends Ren'Py for most people. In the question“What are the best 2D game engines?” Ren'Py is ranked 39th while WiMi5 is ranked 70th. The most important reason people chose Ren'Py is:
Available on Windows, Linux, OSX, iOS and Android.
Specs
Ranked in these QuestionsQuestion Ranking
Pros
Pro Versatile flow diagram script model
WiMi5 integrates a powerful visual scripting solution based on Blackboxes that allows you to create the logic flow of the game. You don't have to code (if you don't want) but you can also do it. WiMi5's actions and behaviors resemble flowcharts where each box represents a function or value, with connections between them representing program flow. This provides a better at-a-glance indication of game logic than a simple list of events, and makes complex behaviors easier to accomplish.
Pro Integrated servers
WiMi5 provides integrated back-end services, with tools available to save game session data, manage rankings, etc.
Pro Free development
The WiMi5 platform is free to use, supported by post-publication royalties.
Pro Built in monetisation tools
WiMi5 provides features to manage in-app purchases and micropayments. Virtual Goods management is integrated into the Logic Editor.
Pro Publication partnerships
WiMi5 maintains partnerships allowing simultaneous publication to a number of Web and mobile stores, all managed through the WiMi5 platform.
Games can also be downloaded and publish it wherever you want: in your own server or with your own partners. Just check the Download feature in the settings of your game.
Pro Cross-platform
Available on Windows, Linux, OSX, iOS and Android.
Pro Active and friendly community
Pro Reasonably good at creating puzzle and point-and-click games
Cons
Con 30% royalties
For filling the engine, publisher, and back-end service roles, WiMi5 takes 30% of game revenues.
Con Not for every genre
While technically capable of creating 2D games in any genre, Ren'Py excels in creating visual novels and has a reasonable feature set for creating puzzle and point-and-click games. Other genres are best tackled by other engines.
Con Outdated Documentation and official built-in tutorials
Unfortunately, you will have to hunt relevant info on how Ren'py script works. The Ren'Py dev has the working tutorials on his Patreon, other than that you might as well just code in Python.