When comparing Defold vs Blender, the Slant community recommends Blender for most people. In the question“What are the best game engines for beginners and non-programmers?” Blender is ranked 9th while Defold is ranked 22nd. The most important reason people chose Blender is:
Blender is licensed under the GPL. Some Blender modules such as the Cycles rendering engine are licensed under the Apache 2.0 license.
Specs
Ranked in these QuestionsQuestion Ranking
Pros
Pro Easy to learn
Defold uses Lua, which is regarded as an easy to learn language by most.
Pro Collaborative
You can invite friends from the dashboard and create games together.
Pro Completely free of charge
Software and online dashboard are free of charge.
Pro Good combination of visual editing + code (Lua)
You can do a lot with drag and drop, but you're not limited -- the code (Lua, which is easy to learn) allows you more power than just visual editing usually gives you.
Pro Easy and fast export for various platforms
Pro Fast results
Going from idea to result is very important for the creative process.
Pro Visual editor
Pro Very performant
Being crossplatform it is important to work on low end devices.
Pro Great community
A very active and friendly community in forums.
Pro Hot reload
It allows you to change scripts in a game while it is running live. Common use-cases is to tweak gameplay parameters or to perform debugging on a running game.


Pro Free and open source
Blender is licensed under the GPL. Some Blender modules such as the Cycles rendering engine are licensed under the Apache 2.0 license.
Pro Has a powerful rendering engine
Blender runs the Cycles path tracing engine under the hood. Cycles is a very powerful rendering engine capable of full path tracing (light fall off, caustics, volumetrics). It is mostly compatible with OpenCL and CUDA rendering, and is implementing mycropolygon displacement features. The upcoming release has a viewport engine called EEVEE whereby you can see and interact with your work in render mode in real time!

Pro Python extensibility
Blender embeds Python 3, which can be used to write add-ons, tools, extend the interface, rig characters and automate tasks.

Pro Powerful animation suite
Blender provides a full rigging system, and automates animation by interpolating between keyframe positions.

Pro Wide import and export format support
Support lots of modern 3D formats including DAE and FBX - ideal for game developers.

Pro Regular release schedule
Releases are made every ~3 months.
Pro Supports both low-poly and hi-poly modeling

Pro Includes video editing & compositing tools
Blender's node-based compositor has comprehensive video sequencing and post-processing features.
Pro Node based modeling support
Pro Sculpting and 3D painting features
Although Blender's 3d painting and sculpting tools (mostly painting) are not at par with specialized software like Substance Painter, ZBrush, or Mari, it is more than capable of getting most jobs done if the user takes the time to learn and understand it.
Pro Keyboard shortcuts
Good keyboard shortcuts for everything. Keep your left hand on the keyboard and your right hand on the mouse.
Pro Very useful for a freelancer
It offers a round solution (it covers many areas and professional fields) for a freelancer, for free, constantly updated, very polished, and allowing high quality results that clients do require. After some learning, it becomes very useful for professional work.
Pro Coherent and streamlined workflow / internal use logic
The trick with Blender is to get used to its usage philosophy, as it keeps consistent through all the application. Once you get it, every feature or addition is learnt naturally, almost effortlessly.
Pro Has a large community
There's a huge community to help you get started immediately.
Pro Very versatile
You don't have to switch between software when you want to do different things. Because modeling, sculpting, composting, video editing etc can all be done in blender.
Cons
Con Google account needed
You need a Google account to develop with Defold.
Con Difficult learning curve
Blender is not a very intuitive 3D modeling software. It has its own ways of doing things, and it is often hard to guess how to achieve simple tasks.
Con Too many possibilities, no unified workflow
The operations are not optimized enough for specific tasks.
Con The physics engine is a bit lagging behind, especially the destruction physics
Con Poor particle system
The Blender particle system can at times be a little limiting and finicky (and buggy) to get working. Even if it can get most straight forward jobs done, it is far from the most advanced system, and could benefit largely from advancements.
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