When comparing Resolume vs MilkDrop 2, the Slant community recommends MilkDrop 2 for most people. In the question“What are the best audio/music visualizers?” MilkDrop 2 is ranked 1st while Resolume is ranked 3rd. The most important reason people chose MilkDrop 2 is:
Plenty of user options to tweak for your system.
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Pros
Pro Midi controllers can be used to control the software
Scene switches, visualization changes and parameter adjustments can be bound to specific keys on a controller.
Pro Intuitive interface
There are helpful real-time indicators for selecting frequency ranges, sliders that show impact, etc. All changes made are immediately visible.
Pro Runs smooth on most modern computers
Plenty of user options to tweak for your system.
Pro A huge preset pack is available
A preset pack with 760 visuals made by Tryptonaut is available. You can find it here
Pro Comes bundled with Winamp
MilkDrop 2 comes as part of Winamp since version 5.5. It's also still available as a separate package if you wish to use it with other software.
Pro Save mp4
Cons
Con Not free
Resolume has two versions, Avenue and Arena, that cost €299 and €699 respectively.
Con No user-friendly way of customizing the visualizations
Short of learning to code there are no ways to change how the presets behave.