When comparing Nix vs Conda, the Slant community recommends Nix for most people. In the question“What are the best Linux package managers?” Nix is ranked 6th while Conda is ranked 16th. The most important reason people chose Nix is:
Nix is a purely functional package management system. This means that the act of building a package does not have side effects, such as destructively updating or deleting files that may be used by other packages.
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Pros
Pro No side effects when building packages
Nix is a purely functional package management system. This means that the act of building a package does not have side effects, such as destructively updating or deleting files that may be used by other packages.
Pro Isolated development environments
Nix allows the creation of project-specific shell and build environments which are isolated from the rest of the system. These environments are defined declaratively to ensure reproducibility.
Pro Can replace docker in some places
Pro Can use multiple versions of the same package
Because of the functional approach it takes, Nix makes it easy for systems to use multiple versions of the same package simultaneously, and ensure that updating or removing a package can't break other packages.
Pro The configuration works on "All machines"
No more of the traditional: "it works on my machine". When it says reproducible, this is the real deal.
Pro Binary installs
They are fast and reliable as they do not need to compile before installation.
Pro Allows for multiple environments
It is great for developers since you can easily switch between complete environments with different versions of packages, for testing and development.
Pro Open source
Conda is open source and on Github, so if you see something wrong you can fix it and submit a patch.
Cons
Con Does not work well for services on non-NixOS systems
When using Nix with anything other than NixOS you can run into difficulties with trying to start up services. For example, you can install docker with Nix, but it won't integrate with the host system's systemd leaving you to handcraft awkward workarounds in order to start the background service that docker requires. This seems like a critical flaw when using Nix on anything that is not NixOS, and it's unfortunate because this affects many of the packages many users would be most interested in using Nix to handle.
Con Steep learning curve
Con Cannot handle filetypes that have different semantics across different versions
While the functional approach that Nix takes is great for sandboxing binary artifacts of packages, it seriously lacks any power in handling configuration files or user data. It's difficult to upgrade and downgrade files where semantics and syntax can change between versions. Especially in Debian/Ubuntu it can cause severe problems where the upgrade process blocks and the user needs to resolve the 3-way merge.
Con Feels slightly over-complicated
Con Doesn't have everything
Conda is relatively new and has a smaller user-base, so the set of packages available is limited.
Con No way to resume downloads
Any download that is canceled or interrupted will have to be started over from the beginning as there is no built in solution for resuming downloads.