When comparing Nix vs XBPS (X Binary Package System), the Slant community recommends XBPS (X Binary Package System) for most people. In the question“What are the best Linux package managers?” XBPS (X Binary Package System) is ranked 4th while Nix is ranked 6th.
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Pros
Pro No side effects when building packages
Nix is a purely functional package management system. This means that the act of building a package does not have side effects, such as destructively updating or deleting files that may be used by other packages.
Pro Isolated development environments
Nix allows the creation of project-specific shell and build environments which are isolated from the rest of the system. These environments are defined declaratively to ensure reproducibility.
Pro Can replace docker in some places
Pro Can use multiple versions of the same package
Because of the functional approach it takes, Nix makes it easy for systems to use multiple versions of the same package simultaneously, and ensure that updating or removing a package can't break other packages.
Pro The configuration works on "All machines"
No more of the traditional: "it works on my machine". When it says reproducible, this is the real deal.
Pro Extremely fast
Pro Can detect incompatibilities
XBPS can detect incompatible shared libraries or dependencies and gives you options before installing.
Pro Can install binaries or build from source
When installing software you can choose to install binaries or build it from source (natively or cross-compiled).
Pro Lots of features
XBPS can not only be used for installing/removing packages, but it can query for package info (such as version, dependencies, size etc), reconfigure packages, report and fix issues by modifying the package database, search for alternatives, manage local repositories and various other useful tools.
Pro Allows partial updates
Pro Written from scratch
Cons
Con Does not work well for services on non-NixOS systems
When using Nix with anything other than NixOS you can run into difficulties with trying to start up services. For example, you can install docker with Nix, but it won't integrate with the host system's systemd leaving you to handcraft awkward workarounds in order to start the background service that docker requires. This seems like a critical flaw when using Nix on anything that is not NixOS, and it's unfortunate because this affects many of the packages many users would be most interested in using Nix to handle.
Con Steep learning curve
Con Cannot handle filetypes that have different semantics across different versions
While the functional approach that Nix takes is great for sandboxing binary artifacts of packages, it seriously lacks any power in handling configuration files or user data. It's difficult to upgrade and downgrade files where semantics and syntax can change between versions. Especially in Debian/Ubuntu it can cause severe problems where the upgrade process blocks and the user needs to resolve the 3-way merge.
Con Feels slightly over-complicated
Con Not just one command to run
It's not a very big drawback, just not as convenient as one command with multiple options to remove and search for apps.
Con Unable to create packages under a non-xbps distribution
Makes maintaining packages a hassle.