When comparing Nix vs Pop!_OS, the Slant community recommends Pop!_OS for most people. In the question“What are the best Linux distributions for desktops?” Pop!_OS is ranked 16th while Nix is ranked 75th. The most important reason people chose Pop!_OS is:
If you're a fan of flat desktop interfaces reminiscent of Material design on Android, you'll like the theme that comes as a default in Pop! OS. The desktop and title bars all use a bright turquoise theme that makes the interface feel happy and borderline retro-chic. I found it to be like something you'd find printed on a ringer t-shirt.
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Pros
Pro No side effects when building packages
Nix is a purely functional package management system. This means that the act of building a package does not have side effects, such as destructively updating or deleting files that may be used by other packages.
Pro Isolated development environments
Nix allows the creation of project-specific shell and build environments which are isolated from the rest of the system. These environments are defined declaratively to ensure reproducibility.
Pro Can replace docker in some places
Pro Can use multiple versions of the same package
Because of the functional approach it takes, Nix makes it easy for systems to use multiple versions of the same package simultaneously, and ensure that updating or removing a package can't break other packages.
Pro The configuration works on "All machines"
No more of the traditional: "it works on my machine". When it says reproducible, this is the real deal.
Pro Pop! makes GNOME look really good
If you're a fan of flat desktop interfaces reminiscent of Material design on Android, you'll like the theme that comes as a default in Pop! OS. The desktop and title bars all use a bright turquoise theme that makes the interface feel happy and borderline retro-chic. I found it to be like something you'd find printed on a ringer t-shirt.
Pro User-friendly installer
The visually appealing and easy to use installer makes dual booting as easy as it can be.
Pro Nice gnome theme dy default
Has nice gnome theme looks really good.
Pro Ready to play games, out of the box
If you still miss how easy it was to just click-install and play games in Windows, Pop! will give you that similar expectation.
Pro A separate NVIDIA version
Most linux distros seem to hate Nvidia's graphics cards e.g. Fedora and OpenSUSE. System76 have decided to be kind. They have decided to form a good relationship with Nvidia fans and Nvidia itself. By creating a separate installation media that is dedicated for providing support to Nvidia's graphics cards. Even going as far as putting Nvidia's driver updates on Pop!_Shop for users to easily access and install.
Pro Optimized for modern hardware
Whereas normally, to use a brand new computer with a Linux OS, you would typically try to use unstable and sometimes buggy drivers - or struggle without hardware support until a stable release comes along.
Pro Made by a hardware seller
System76 is a hardware company. It configures machines to ship with Linux pre-installed. This means its entire business model centers around delivering a quality desktop Linux experience.
As a result, the company pours more attention onto the desktop. It can fix visual issues and may be able to provide a smoother overall experience than you would have installing a different version of Linux on your machine yourself. Providing Pop!_OS also empowers System76 to make certain fixes for users directly rather than having to coordinate with Canonical or the broader Ubuntu community.
Cons
Con Does not work well for services on non-NixOS systems
When using Nix with anything other than NixOS you can run into difficulties with trying to start up services. For example, you can install docker with Nix, but it won't integrate with the host system's systemd leaving you to handcraft awkward workarounds in order to start the background service that docker requires. This seems like a critical flaw when using Nix on anything that is not NixOS, and it's unfortunate because this affects many of the packages many users would be most interested in using Nix to handle.
Con Steep learning curve
Con Cannot handle filetypes that have different semantics across different versions
While the functional approach that Nix takes is great for sandboxing binary artifacts of packages, it seriously lacks any power in handling configuration files or user data. It's difficult to upgrade and downgrade files where semantics and syntax can change between versions. Especially in Debian/Ubuntu it can cause severe problems where the upgrade process blocks and the user needs to resolve the 3-way merge.
Con Feels slightly over-complicated
Con 64-bit only
Some older PCs still have 32 Bit processors. This limitation will be a major con for those who use an older PC since they will not be able to install, run it in a VM or live media
