When comparing GNU Guix vs Bedrock, the Slant community recommends Bedrock for most people. In the question“What are the best Linux distributions for desktops?” Bedrock is ranked 35th while GNU Guix is ranked 58th.
Specs
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Pros
Pro Can setup a shell which has exactly the defined libraries available
A method which works across languages and provides a reproducible programming environment.
Pro Can always roll back to a safe state
Guix creates new profile generations for each operation. If anything goes wrong, a simple --roll-back gets you immediately back to the previous, working, generation. Because it is a purely functional package management system, generations don't affect each other, so you're back to the exact same state as before : still working.
Pro Can create independent packages
Guix pack creates packages which do not need Guix to be run.
Pro No side effects when building packages
Guix is a purely functional package management system. This means that the act of building a package does not have side effects, such as destructively updating or deleting files that may be used by other packages.
Pro Can build containers right-away, from docker to tarballs
See guix pack --help and here.
Pro Easy to add your own packages
The clean and declarative syntax makes it easy to define new packages by using an existing one as an example.
Pro Doesn't require root privileges
Normal users can install packages on a Guix-enabled system, or even run their own Guix instance if the system isn't Guix-enabled.
Pro Choose your init system
Pro Choose your package manager
Pro Virtually every pro from every linux distro
Since Bedrock lets you pick and choose the best parts from each distro, every single pro from each distro applies to Bedrock.
Pro Pick and choose what you want from other distros
Want Debian's stable base and Arch's pacman for bleeding edge packages?
Want the security of Qubes OS and Gentoo's portage?
With the correct setup all this can be achieved.
Cons
Con Updates take a long time
It's gotten better over time but both updating Guix itself and updating the installed packages can take a long time.
Con Cannot handle filetypes that have different semantics across different versions
While the functional approach that Guix takes is great for sandboxing binary artifacts of packages, it seriously lacks any power in handling configuration files or user data. It's difficult to upgrade and downgrade files where semantics and syntax can change between versions.
Con Often increases boot times
Since Bedrock has to load the strata before handing control to the chosen init system, it can make booting your machine take longer.
Con Difficulty setting up
Bedrock can be challenging to setup properly with the correct strata.
