When comparing NoSleep vs ClamXav, the Slant community recommends NoSleep for most people. In the question“What are the best Mac OSX apps for someone that's new to Apple?” NoSleep is ranked 26th while ClamXav is ranked 28th. The most important reason people chose NoSleep is:
The laptop will not sleep even if you close the lid, but the display will sleep. If your display cannot sleep, simply lower the brightness until it goes dark & turns off.
Ranked in these QuestionsQuestion Ranking
Pros
Pro Lets you close the lid of a laptop
The laptop will not sleep even if you close the lid, but the display will sleep. If your display cannot sleep, simply lower the brightness until it goes dark & turns off.
Pro Monitor directories easily
The Sentry Feature monitors specific directories 24/7 as well as removable media which includes USB & external drives, all those .dmg files you open when installing apps etc. I add all directories that files are downloaded as a "screening" process.
Pro Lean
Not overly invasive or processor hungry as other antivirus programs
Cons
Con Discontinued development
Latest release was November 15th, 2014.