When comparing Letters from Whitechapel vs Zombicide, the Slant community recommends Zombicide for most people. In the question“What are the best scary board games to play around Halloween?” Zombicide is ranked 6th while Letters from Whitechapel is ranked 7th. The most important reason people chose Zombicide is:
There are additional sets available ranging from new survivor cards to different enemy miniatures, more game tiles, etc. There is also a medieval version - Black Plague - which offers an alternate settings and slight rule/weapon changes.
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Pros
Pro Avoids advantage to any player
A lot of co-op games have a problem with one player getting an advantage, this is called an alpha player. Letters from Whitechapel avoids this issue by rotating the Head of Investigation (a player who leads the rest of his co-op partners) each round, this way avoiding one player who has too much control of the game for too long.
Pro Satisfying asynchronous play
Many games try to do asynchronous gameplay but often do not get it right. Luckily Letters for Whitechapel nailed the gameplay with a well balanced role of Jack the Ripper, who often only narrowly escapes the police, which gives a feeling of tension to the one player who could have an advantage if not balanced correctly.
Pro Lots of expansions
There are additional sets available ranging from new survivor cards to different enemy miniatures, more game tiles, etc.
There is also a medieval version - Black Plague - which offers an alternate settings and slight rule/weapon changes.
Pro Replayability
Prison Outbreak, Toxic City Mall, and Angry Neighbors are all expansion packs you can add to the base game. Extras such as Dog Companions, Zombie Dogz, and VIP (very infected people) add new figures, figures, and equipment. There is also a new version: Black Plague which takes place in a medieval setting (expansion coming in June)
Pro Quality components
The game comes with a bunch of miniatures, all molded out of plastic and have nice detailing as well as individual looks. The cardboard game cards, etc also have a solid think feel to them as well as colorful and illustrative art printed on them with the cards even being double sided. The amount of pieces and the quality of there craftsmanship definitely give a feeling of robustness that earns the game its high price ($89 retail).
Pro Co-op play
Teamwork is essential to completing your objectives - some players will level up towards ranged combat, while others move about quickly. Not all players will be able to open the required doors, and you level up individually but don't let one player level up much faster than the others - zombies seem to thrive off success.
Cons
Con Slow beginning
The beginning of the game is the poorest part as it is slow to setup and can be confusing, especially to new players.
Con Error filled rulebook
The packaged rulebook is not only filled with errors and typos but is also missing a lot of pertinent information to the gameplay. Luckily there is an updated version as a PDF download on the publishers site that has the extra content the printed version is missing.