Dropwizard vs Flask
When comparing Dropwizard vs Flask, the Slant community recommends Flask for most people. In the question“What are the best backend web frameworks?” Flask is ranked 4th while Dropwizard is ranked 28th. The most important reason people chose Flask is:
Flask is very easy to get up and going, with vanilla HTML or with bootstrap pieces. It doesn't take much lines of Python to load Flask to get headers working, etc, and since it's all modular you don't have to have something you don't want in your application.
Specs
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Pros
Pro Enhanced productivity and less timewasting
The application can be run and debugged from the IDE without the need to recompile or redeploy the WAR file. This is because a Dropwizard web application creates on main program which starts the jetty container.

Pro Application metrics integrated into the framework
Dropwizard comes with application metrics integrated out of the box. These metrics provide a lot of useful information such as request/response time.
For example, to get the execution time of a method, the @Timed
annotation is used.

Pro Quick project bootstrap
Starting a project with Dropwizard si very easy and bootstraping is quick and painless. All that's needed is a single dependency added in the pom.xml
file and it's ready to go.
Pro Minimalist without losing power
Flask is very easy to get up and going, with vanilla HTML or with bootstrap pieces. It doesn't take much lines of Python to load Flask to get headers working, etc, and since it's all modular you don't have to have something you don't want in your application.
Pro Lots of resources available online
Flask is one of the most popular Python web frameworks, if not the most popular one. As such, there's plenty of guides, tutorials, and libraries available for it. A large number of important Python libraries, such as SQLAlchemy have libraries for Flask, which add valuable bindings to make the development process and the integration between these libraries and Flask as easy as possible.
Pro Extremely easy to build a quick prototype
Even though it's pretty minimalistic out of the box, Flask still provides the necessary tools to build a quick prototype for a web app right after a fresh install. With all the main components pretty much packed in the flask
package, building a simple web app in a single Python file is as easy as it gets.
Pro Very flexible
Flask gives developers a lot of flexibility in how they develop their web applications.
For example, the choice of not having an ORM, but instead choosing one suited to the task, or another area where Flask gives a lot of options to developers is the templating. They can use Jinja2, Flask's default templating language or choose from a number of different templating languages they desire.
Pro Great documentation
The official documentation is very thorough and complete. Everything is explained in-depth and followed by extremely well-explained tutorials that tackle real-world problems.
Pro Able to use ORM or "true SQL"
Cons
Con Does not allow a lot a freedom of choice
Dropwizard removes a lot of freedom that the developer may have with other frameworks because of the fact that it tries to do everything itself. It chooses the best Java libraries for the job required, without allowing the developer much choice.
Con Not async-friendly
Flask is explicitly not designed to handle async programming.
Con Setting up a large project requires some previous knowledge of the framework
Setting up a large project with Flask is not that easy considering how there's no "official" way of doing it. Blueprints are a useful tool in this regard but require some additional reading and are a bit tricky to get right for a beginner.
The lack of some defaults can also be problematic. Having to choose between different libraries for a certain task is never easy, especially if you have never worked with Flask before.
Con Threadlocals and globals used everywhere
The default way of creating applications in flask makes it hard to use reusable and clean code.
Con HTML-oriented, not API-oriented
Not necessarily designed for making APIs, though that is possible
