When comparing Koa vs Actix, the Slant community recommends Actix for most people. In the question“What are the best backend web frameworks?” Actix is ranked 22nd while Koa is ranked 33rd.
Specs
Ranked in these QuestionsQuestion Ranking
Pros
Pro Generator support from ground up
Using generators (a bleeding edge feature, even for Node.js) would clean up your code from the mess caused by all those callbacks; making your code more manageable.
Pro Extremely lightweight
Koa is very lightweight with just 550 lines of code.
Pro async/await keywords are supported and has transcended beyond generator functions
Generators functions are of course a huge plus, but at the time Koa team has transcended generations functions and shifted towards async/await style programming. It has made the Koa best framework available in the market.
Pro Development team has a proven track record
Koa is developed by the team behind a widely used node.js framework (express.js).

Pro Built for ES6
Pro Blazingly fast
Pro Feature-rich
Actix provides a lot of features out of box. WebSockets, HTTP/2, pipelining etc
Pro Type-safe
Forget about stringly typed objects, from request to response, everything has types
Pro Extensible
Easily create your own libraries that any Actix application can use
Cons
Con Community is relatively small
Con Not compatible with express style middleware
Koa uses generators which are not compatible with any other type of Node.js framework middleware.
Con Has no routes separated by HTTP method or URL pattern
Con Wrong Middle ware, security issue
