When comparing Visual Studio with the Python Tools extension vs Eclipse with PyDev, the Slant community recommends Eclipse with PyDev for most people. In the question“What are the best Python IDEs or editors?” Eclipse with PyDev is ranked 22nd while Visual Studio with the Python Tools extension is ranked 38th. The most important reason people chose Eclipse with PyDev is:
Eclipse has a large and active community, which has resulted in a wide variety of plugins.
Specs
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Pros
Pro Autocompletion based on variable types
Has smart autocompletion based on variable types
Pro Cloud storage through VS Online
Your Visual Studio Online account gives you a place to store your code, backlog, and other project data with no servers to deploy, configure, or manage.
Pro Web based interface to track project progress
In agile development teams one really needs features such as product backlogs where you can assign features to team mates and track their progress on them. VS provides a web based interface for you to track your team's complete progress on the project.
Pro Can be extended to have additional features through plugins
Eclipse has a large and active community, which has resulted in a wide variety of plugins.
Pro Feature rich including Django integration
Django Integration, Auto code completion, Multi language support, Integrated Python Debugging, code analysis, code templates ,smart indent, bracket matching, error markup, source control integration, code folding, UML Editing and viewing, and unit test integration.
Pro Good integration of interactive python console even in debugging mode
Pro Handles non-Python components well
If your project includes non-Python pieces (ie. Javascript, CSS, UML, etc) Eclipse tends to provide much better support for these than IDEs focused exclusively on Python.
Pro Can use different environments for different projects
It's very handy for managing multiple projects that each use their own virtualenv or conda environment, you can assign a different interpreter to each project and they will handle things like code completion correctly.
Pro Good font rendering
Because Eclipse is based on SWT, it uses the native font rendering and thus looks better than other IDEs on some Linux systems, where the Java font rendering is not optimal.
Pro One of the few that can debug Jython code
It handles both Jython and CPython.
Cons
Con Windows only
Visual Studio is only available on Windows, though there is now a cross-platform derivation of Visual Studio named Visual Studio Code. It is has less features and is more of a code editor than an IDE.
Con Proprietary
Visual Studio is a proprietary software.
Con Just plugin for python, not full editor
It useful only if you use python as additional(secondary) language in your project on Eclipse
Con Plugins can be unstable
Though there are plenty of plugins to choose from, they aren't always reliable. Some aren't maintained, bug fixes can be slow, and you may need to download plugins from multiple sources.