When comparing Visual Studio with the Python Tools extension vs Light Table, the Slant community recommends Light Table for most people. In the question“What are the best Python IDEs or editors?” Light Table is ranked 25th while Visual Studio with the Python Tools extension is ranked 36th. The most important reason people chose Light Table is:
With LT's inline evaluation, you don't have to re-compile your whole source file. Each time you want to see an output, all you have to do is hover your cursor over the line you'd like to evaluate and press `ctrl+enter`; LT will evaluate that line of code for you.
Specs
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Pros
Pro Autocompletion based on variable types
Has smart autocompletion based on variable types
Pro Cloud storage through VS Online
Your Visual Studio Online account gives you a place to store your code, backlog, and other project data with no servers to deploy, configure, or manage.
Pro Web based interface to track project progress
In agile development teams one really needs features such as product backlogs where you can assign features to team mates and track their progress on them. VS provides a web based interface for you to track your team's complete progress on the project.
Pro Inline evaluation
With LT's inline evaluation, you don't have to re-compile your whole source file. Each time you want to see an output, all you have to do is hover your cursor over the line you'd like to evaluate and press ctrl+enter
; LT will evaluate that line of code for you.
Pro Your code runs live as you write it
The "Watches" feature lets you see your code running live as you type it. This means that you can debug your code live while writing it, which leads to considerably less programming errors.
Pro Plugin manager available
LT has a plugin manager built directly inside of it. This plugin manager connects to LT's own registry of plugins, so whenever you want assistance while writing your HTML, JS, or even Python, just open up the plugin manager, search for it, and click the little install button beside it's name. Your plugin will then be installed.
Cons

Con Windows only
Visual Studio is only available on Windows, though there is now a cross-platform derivation of Visual Studio named Visual Studio Code. It is has less features and is more of a code editor than an IDE.

Con Proprietary
Visual Studio is a proprietary software.
