When comparing Spyder vs iTerm2, the Slant community recommends iTerm2 for most people. In the question“What are the best developer tools for Mac OSX?” iTerm2 is ranked 2nd while Spyder is ranked 26th. The most important reason people chose iTerm2 is:
iTerm has autocomplete features built in. It remembers your past commands and when you are writing something on the terminal, simply pressing `Control-;` it will show you a drop down menu of suggestions from which to choose.
Specs
Ranked in these QuestionsQuestion Ranking
Pros
Pro Free and open-source
Released under the MIT license.
Pro Graph plotting support
Spyder can plot graphs and provide the list of all variables.
Pro Relatively lightweight
Pro Powerful autocompletion
Spyder's autocomplete features are made possible by a library called rope which gives Spyder powerful autocompletion.
Pro Has support for Vim bindings via plugin support
Aside from being an open sourced, actively developed IDE, vim key-binding support is also available. If you remember Pydee - this is it, albeit with a new name.
Pro Helps you to use documentation
Pro Enables to write consistent code
Pylint integration enables to check the code for PEP8 style guide and detect errors.
Pro Has cross platform support - Linux, Mac, and even Windows
Spyder (formerly Pydee) has support for all of the major operating platforms - Linux, Mac, and even Windows.
Pro Intuitive interface
Pro Good GitHub project
Pro Excellent variable explorer
Dynamic variable explorer with editor and visualizer
Pro Completely Python
Pro Autocomplete is built-in
iTerm has autocomplete features built in. It remembers your past commands and when you are writing something on the terminal, simply pressing Control-;
it will show you a drop down menu of suggestions from which to choose.
Pro Extremely customizable
Other than being able to customize the various shortcuts, iTerm2 also lets you customize the colorscheme, font, transparency, etc.
Pro Fine tuning for fonts
It's possible to choose a font and adjust vertical and horizontal spacing.
Pro Complete out of the box
Unlike most terminal emulators, iTerm2 comes with a pretty complete set of features. It has built-in search, autocompletion, tabbed navigation, Growl support and even a built-in clipboard manager for various API keys and such.
Pro Any key can be mapped to any function
Using the Preferences Menu you can set up hotkeys to map virtually any action you can think of to a single key or a combination of them. This is extremely helpful as it allows you to use shortcuts to edit commands you are typing in the terminal and while most terminal emulators have shortcuts for this sort of thing, few of them let you define your own.
Pro Can immediately open files inside a text editor
You can Ctrl+Click on a file path to open said file in a text editor.
Pro Active maintainers
Issues resolved fast by quality contributors.

Pro Works well with powerline fonts
Pro Supported by many applications as a terminal app selection
If an application has terminal integration, there is high probability it allows iTerm2 to be selected.
Pro Supports mouse actions
Has support for mouse actions like clicking, dragging, selecting, etc.
Pro Can be configured as a drop-down terminal
Can be configured to work as a drop down terminal like Quake.
Pro Completely free and open source
iTerm2 is completely free and open source. It's released under the GPLv2 license.
Pro Works well with tmux
The great mouse and clipboard support that are built-in go really well with tmux.
Pro Intuitive
Pro Split panes
Easy to split panes to either horizontal or vertical sections. Makes it easy to observe multiple console windows.
Pro You only need to type in commands once
iTerm2 can store up to 4M of history of commands you already used. This, coupled with the built-in search features makes it possible to type a command only once and then search for it through the history for subsequent uses.
Pro Cmd+D to split plane vertically
Very handy to use multi-tab.
Pro Works perfect with Oh My Zsh
It's a perfect base to add Oh My Zsh on top of it and enjoy a lot of themes and a really pleasant look and feel.
Pro Cmd+Shift+I to Input all
Wanna SSH your server from multiple tabs, here you go.
Cons
Con Not beautiful
The default theme is not beautiful. And there are not many themes.
Con The documentation is poor when it comes to debugging
Not a lot of information about debugging is available in the documentation.
Con Consumes a lot of memory
If you're working with large data, especially arrays, another IDE should be considered as spyder uses at least 200-300Mb of memory.
Con Not quite as fast as Alacritty or Kitty
Comparing these 3 terminals on the same machine/config, iTerm stands out as the slowest of the bunch. The difference may not be noticeable to all users.
Con Doesn't support Snow Leopard 10.6.8
Some people still use Snow Leopard or other 32-bit systems.
Con Doesn't support RTL
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