When comparing Spyder vs MacDown, the Slant community recommends MacDown for most people. In the question“What are the best developer tools for Mac OSX?” MacDown is ranked 4th while Spyder is ranked 25th. The most important reason people chose MacDown is:
MacDown is a free and open source editor influenced by [Mou](http://25.io/mou/). It's released under the MIT license.
Specs
Ranked in these QuestionsQuestion Ranking
Pros
Pro Free and open-source
Released under the MIT license.
Pro Graph plotting support
Spyder can plot graphs and provide the list of all variables.
Pro Enables to write consistent code
Pylint integration enables to check the code for PEP8 style guide and detect errors.
Pro Powerful autocompletion
Spyder's autocomplete features are made possible by a library called rope which gives Spyder powerful autocompletion.
Pro Has cross platform support - Linux, Mac, and even Windows
Spyder (formerly Pydee) has support for all of the major operating platforms - Linux, Mac, and even Windows.
Pro Helps you to use documentation
Pro Intuitive interface
Pro Relatively lightweight
Pro Has support for Vim bindings via plugin support
Aside from being an open sourced, actively developed IDE, vim key-binding support is also available. If you remember Pydee - this is it, albeit with a new name.
Pro Good GitHub project
Pro Excellent variable explorer
Dynamic variable explorer with editor and visualizer
Pro Completely Python

Pro Free and open source
MacDown is a free and open source editor influenced by Mou. It's released under the MIT license.

Pro Real-time split-screen preview
MacDown's main view is split into two panels. The user types on the left and the Markdown is rendered on the fly in the right panel. This helps users to better understand the way they are formatting their document.
Pro Markdown previews can be customized with CSS
You can use a CSS file to customize the rendered output and the file preview you are working on will display the rendered Markdown with the custom CSS styling on top.

Pro Supports syntax highlighting in fenced code blocks
MacDown has syntax highlighting support for various languages when writing code in fenced code blocks.
Pro Good auto-completion
MacDown has a good built-in auto-completion engine for Markdown symbols.

Pro Support for GFM
Pro Ideal for day-to-day programmers' work and MarkDown novices alike
Using MacDown for the notorious README.md use case gets you going without reading any manual or requiring any configuration values. Think of it as a sort of TextEdit for MarkDown files. Thus its shortcomings - neither powerful nor versatile - turn out to be a PRO for novices trying to jump on the MarkDown bandwagon. Open its help and you'll immediately find yourself editing the MacDown's MarkDown help file, a MarkDown primer with some MacDown menus and configuration added.
Pro Linking between pages
Unlike a few other editors, MacDown lets you link between markdown pages.
Pro Tool bar with most used markdown shortcuts
This is especially useful for Markdown novices
Cons
Con Not beautiful
The default theme is not beautiful. And there are not many themes.
Con The documentation is poor when it comes to debugging
Not a lot of information about debugging is available in the documentation.
Con Consumes a lot of memory
If you're working with large data, especially arrays, another IDE should be considered as spyder uses at least 200-300Mb of memory.
Con Not very versatile
MacDown is not very powerful or versatile. It's not customizable or extendable. This is what makes it so simple, but it's not for people who want more from their tools.
Con Frequently fails to update the display and/or flat out hangs
Must often restart MacDown.
Con The Markdown preview is rather heavy on the CPU
The Markdown preview needs a lot of resources to keep rendering on-the-fly after each keystroke. A single keystroke in the editor panel may trigger up to 5 seconds of max-CPU usage.
