When comparing PHP vs Flask, the Slant community recommends Flask for most people. In the question“What are the best backend web frameworks?” Flask is ranked 7th while PHP is ranked 52nd. The most important reason people chose Flask is:
Flask is very easy to get up and going, with vanilla HTML or with bootstrap pieces. It doesn't take much lines of Python to load Flask to get headers working, etc, and since it's all modular you don't have to have something you don't want in your application.
Specs
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Pros
Pro One of the most common languages
According to the 2015 Stack Overflow Developer Survey (26,086 people surveyed), PHP was the 5th most popular/used language at 29.7%.
Pro Lots of tutorials online
Pro Used by most common CMS platforms
Many clients are looking for an easy-to-update web site that's flexible and free. Drupal and Wordpress fill those needs very well.
Pro Most prominent language for web applications
Part of the de facto standard web application stack.
Pro Great third-party package manager
PHP standard library is somewhat subpar, but if you need plugins, language features, composer has them all( you can even puzzle together a custom framework from composer).
Pro Fast
Since 7.x was released, PHP has become a pretty fast language.
Pro Lots of PHP frameworks available which help with development
PHP people love frameworks, and with frameworks such as Laravel, you can build a web app or API really fast (Facades, ORMs, scaffolding etc.)
Pro Great documentation
Pro Minimalist without losing power
Flask is very easy to get up and going, with vanilla HTML or with bootstrap pieces. It doesn't take much lines of Python to load Flask to get headers working, etc, and since it's all modular you don't have to have something you don't want in your application.
Pro Lots of resources available online
Flask is one of the most popular Python web frameworks, if not the most popular one. As such, there's plenty of guides, tutorials, and libraries available for it. A large number of important Python libraries, such as SQLAlchemy have libraries for Flask, which add valuable bindings to make the development process and the integration between these libraries and Flask as easy as possible.
Pro Extremely easy to build a quick prototype
Even though it's pretty minimalistic out of the box, Flask still provides the necessary tools to build a quick prototype for a web app right after a fresh install. With all the main components pretty much packed in the flask
package, building a simple web app in a single Python file is as easy as it gets.
Pro Very flexible
Flask gives developers a lot of flexibility in how they develop their web applications.
For example, the choice of not having an ORM, but instead choosing one suited to the task, or another area where Flask gives a lot of options to developers is the templating. They can use Jinja2, Flask's default templating language or choose from a number of different templating languages they desire.
Pro Great documentation
The official documentation is very thorough and complete. Everything is explained in-depth and followed by extremely well-explained tutorials that tackle real-world problems.
Pro Able to use ORM or "true SQL"
Cons
Con Poorly designed language
Despite its widespread use, PHP is generally looked upon poorly from a design point of view. The consistency of function names and function argument order, lazily and borderline non-functional implementation of object oriented programming, can only receive requests via POST methods, slow version adoption (the PHP you learn right now may not work on every webserver you'll work on), and a focus on "hacking things together" rather than "doing it right". These are all very common complaints when it comes to working with PHP. While not a bad language to learn, PHP is not at all a good language to learn first, as it will probably teach bad habits.
Con Immense catalog of insecure frameworks
The most serious security problems in websites on the web today are almost universally found in popular PHP frameworks, CMS platforms, libraries and code samples, almost all stemming from poor language design, bad tutorials and awful resources.
Con After python, probably one of the worst languages ever
Con Poorly designed language, awful syntax & luckily on the decline
Nobody in their right mind is using PHP for new software, if you decide to learn it as your first language you'll be stuck working in teams with old developers who have had no interest in the computer programming field since they landed their first job while maintaining some 2000 era archaic website codebase.
Con Most tutorials are out of date
A lot of very bad tutorials are still widely circulated among beginners, and these tutorials teach very poor programming practices.
Con Most resources are poorly-written
Few resources exemplify the "correct" or secure use of features.
Con Interpreter being too permissive
If you forget the dollar sign, the variable name will be converted to a string.
Con Not async-friendly
Flask is explicitly not designed to handle async programming.
Con Setting up a large project requires some previous knowledge of the framework
Setting up a large project with Flask is not that easy considering how there's no "official" way of doing it. Blueprints are a useful tool in this regard but require some additional reading and are a bit tricky to get right for a beginner.
The lack of some defaults can also be problematic. Having to choose between different libraries for a certain task is never easy, especially if you have never worked with Flask before.
Con Threadlocals and globals used everywhere
The default way of creating applications in flask makes it hard to use reusable and clean code.
Con HTML-oriented, not API-oriented
Not necessarily designed for making APIs, though that is possible