When comparing Logitech MX Anywhere 2 Wireless Mobile Mouse vs Logitech Signature M650, the Slant community recommends Logitech Signature M650 for most people. In the question“What are the best wireless mice for programmers with small hands?” Logitech Signature M650 is ranked 3rd while Logitech MX Anywhere 2 Wireless Mobile Mouse is ranked 4th. The most important reason people chose Logitech Signature M650 is:
In combination with a button on the left side, horizontal scrolling with the scrollwheel can be configured in the software.
Specs
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Pros
Pro Rechargeable battery
The battery is rechargeable and lasts up to two months on a single charge.
Pro Tracks well on all surfaces
This mouse tracks really well on almost all surface types (including glass).
Pro Vertical and Horizontal scrolling
In combination with a button on the left side, horizontal scrolling with the scrollwheel can be configured in the software.
Pro Quiet
Less click noise.
Pro Bluetooth or USB
Pro Bolt receiver
The bolt receiver was only available on the more expensive models in the past.
Cons
Con Scroll can sometimes jump around
The wheel can sometimes have an issue with "phantom scroll". It may cause the page to jump around/scroll some on its own.
Con Not compatible with Unifying receivers
Not compatible with Logitechs older Unifying receivers.
