Here’s the Deal
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When comparing PyAutoGUI vs Sikuli Slides, the Slant community recommends PyAutoGUI for most people. In the question“What are the best generic (image based) GUI functional test frameworks?” PyAutoGUI is ranked 4th while Sikuli Slides is ranked 6th. The most important reason people chose PyAutoGUI is:
Requires scrot but else it's almost pure Python code.
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Pros
Pro Python package with few system dependencies
Requires scrot but else it's almost pure Python code.
Pro Cross-platform
Pro Open source
Sikuli slides is free and open source. The source code is hosted on GitHub and is freely distributed under the MIT license.
Cons
Con Only pixel-perfect image matching
When locating element by image comparison, it must be pixel perfect, meaning that any platform/machine change in the UI even very minor will break your script.
No cons yet!