When comparing Flask vs Slim, the Slant community recommends Flask for most people. In the question“What are the best web frameworks to create a web REST API?” Flask is ranked 7th while Slim is ranked 12th. The most important reason people chose Flask is:
Flask is very easy to get up and going, with vanilla HTML or with bootstrap pieces. It doesn't take much lines of Python to load Flask to get headers working, etc, and since it's all modular you don't have to have something you don't want in your application.
Specs
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Pros
Pro Minimalist without losing power
Flask is very easy to get up and going, with vanilla HTML or with bootstrap pieces. It doesn't take much lines of Python to load Flask to get headers working, etc, and since it's all modular you don't have to have something you don't want in your application.
Pro Lots of resources available online
Flask is one of the most popular Python web frameworks, if not the most popular one. As such, there's plenty of guides, tutorials, and libraries available for it. A large number of important Python libraries, such as SQLAlchemy have libraries for Flask, which add valuable bindings to make the development process and the integration between these libraries and Flask as easy as possible.
Pro Extremely easy to build a quick prototype
Even though it's pretty minimalistic out of the box, Flask still provides the necessary tools to build a quick prototype for a web app right after a fresh install. With all the main components pretty much packed in the flask
package, building a simple web app in a single Python file is as easy as it gets.
Pro Very flexible
Flask gives developers a lot of flexibility in how they develop their web applications.
For example, the choice of not having an ORM, but instead choosing one suited to the task, or another area where Flask gives a lot of options to developers is the templating. They can use Jinja2, Flask's default templating language or choose from a number of different templating languages they desire.
Pro Great documentation
The official documentation is very thorough and complete. Everything is explained in-depth and followed by extremely well-explained tutorials that tackle real-world problems.
Pro Able to use ORM or "true SQL"
Pro Well organized and thorough documentation
Slim's documentation is well organized and detailed, every concept is thoroughly explained and it is very helpful for both advanced users and beginners.
Pro A good starting point
Slim is minimal and that is a good thing if you want to start from there. It can be easily extended and even supports popular packages that are used in Laravel (like Illuminate\Database (eloquent)) for example.
Pro REST based
REST fans will love the REST based architecture.
Pro Supports tie-ins for Rack-like middleware
Rack is an interface used in Ruby frameworks used to group and order modules, which most of the time are Ruby classes, and specify between them.
Slim uses a simple concept for it's middleware. By wrapping HTTP requests and responses it unifies the middleware into a single method call.
Pro Useful classes
Contains classes for managing requests, responses, cookies, logging, views, HTTP caching, and more.
Pro Flexible
Slim doesn't demand that you stick to a fixed folder structure. As long as you load Slim the right way you can do anything from there the way you like it.
Pro Extremely lightweight
Paired with swoole it's a micro service powerhouse.
Pro Open source
The Slim Framework is open source and is released under the MIT public license
Pro Extremely customizable
You can add any dependency, package or class that you want to use as a contained dependency.
Pro Supports Php 5.3 and PHP 7
Pro Makes it easy to understand the way some abstract functions and classes are built
In Django most things are abstracted, you just call some function or class without knowing how they were built, but with Slim, you end up understanding the way some abstract functions and classes are built.
Pro Hooks for executing code at different points in its life-cycle
Slim supports code hooks for executing functions at different points in time during the application's lifecycle.
Cons
Con Not async-friendly
Flask is explicitly not designed to handle async programming.
Con Setting up a large project requires some previous knowledge of the framework
Setting up a large project with Flask is not that easy considering how there's no "official" way of doing it. Blueprints are a useful tool in this regard but require some additional reading and are a bit tricky to get right for a beginner.
The lack of some defaults can also be problematic. Having to choose between different libraries for a certain task is never easy, especially if you have never worked with Flask before.
Con Threadlocals and globals used everywhere
The default way of creating applications in flask makes it hard to use reusable and clean code.
Con HTML-oriented, not API-oriented
Not necessarily designed for making APIs, though that is possible
Con Very little consistency among different versions
There have been quite some changes that break the compatibility between Slim 2 and Slim 3. Even if you learned how to work with the Slim 2, you will find that Slim 3 requires re-training.
Con Dependency injection is too weak
It is not really dependency injection, but just a configurable container.
Con Needs strong bases to create dependencies
The dependency container schema of Slim is one of the biggest PROS and CONS of the framework. It is true that this schema brings so much flexibility to add anything, but another thing that is true is that you need to have strong bases of patterns, and an extensive knowledge of your libraries to convert it into a Slim dependency.
Con Too minimal
While it's true that Slim is a microframework, it's still too minimal. When used for throwaway projects or simple prototypes, it's perfect. But in the long run, it becomes less and less useful and you end up in implementing a full custom framework in trying to tackle all the missing features.