When comparing Guile vs C#, the Slant community recommends C# for most people. In the question“What are the best general-purpose programming languages?” C# is ranked 3rd while Guile is ranked 5th. The most important reason people chose C# is:
The Visual Studio IDE offers one of the best development environments. The [Community Edition](https://visualstudio.microsoft.com/vs/community/) can be used for free.
Ranked in these QuestionsQuestion Ranking
Pro GNU's official extension language
Chances are a system running enough GNU software will already have it installed.
Pro Easy to customize and extend applications
Guile makes it easy for users of your application to write extensions without needing to understand the plumbing of your program.
Pro Excellent documentation
The documentation provides conceptual overviews, tutorials, and a detailed reference for all commands, functions, and operators.
Pro Visual Studio
The Visual Studio IDE offers one of the best development environments. The Community Edition can be used for free.
Can be designed visually with the Visual Studio designer for traditional Windows forms, WPF, or Web forms.
.NET offers rich functionality.
Pro Can be used in a variety of fields
with Xamarin for Mobile (ios, android)
with .net core asp for server (linux, windows)
with .net core for desktop (windows, mac)
with mono for desktop (windows, linux)
with blazor for web client with webassembly.
However, it is not considered top for any of those categories
top choice for windows desktop with .net framework
top choice for Unity
.net 5 will unify frameworks similar to JVM (just one)
Pro It is a C like language.
Being a C like language counts in favor for it as a general purpose programming language, given the ease of using existing skills to pick up this language easily.
there are other superior languages that could be used as a general purpose, such as: F#, Haskell, but the complexity of those languages, being functional, make them strange to the usual C Syntax.
C# is better than C whenever garbage collection, Objects, classes, data access, are needed. But C is going to be the choice when hardware access and performance are paramount.
Pro 3rd Party support
Lot's of tools and libraries available.
Con Weak copyleft
Con Learning curve
For a beginner the .NET framework can be daunting, the rich functionality means that things often can be done in several ways.
Con Microsoft will mess up with the Visual studio installation
And all of a sudden you'll need to reinstall the entire thing just because it stopped working.
Microsoft assumes that every workstation is connected to the Internet then it is always pushing updates.
Con Very large runtime
Cannot be used for embedded programming