When comparing Spectre vs Skeleton, the Slant community recommends Skeleton for most people. In the question“What is the best CSS framework?” Skeleton is ranked 7th while Spectre is ranked 9th.
Ranked in these QuestionsQuestion Ranking
Works well on any device.
Contains only the basics, no extra fluff.
Pro Open source
Spectre is used through Github, and is open source.
Very clean design compared to bootstrap.
Pro Mobile ready
Spectre can be used to create mobile websites easily. With all the regular built in elements (buttons, menus, grids etc).
Pro Responsive grid
Pro Style agnostic
Pro Vanilla CSS
No bells and whistles for Skeleton, it's just CSS.
Pro Media queries
Con Not maintained anymore
No active development for two years.