When comparing Clojure vs ClojureScript, the Slant community recommends Clojure for most people. In the question“What is the best programming language to learn first?” Clojure is ranked 11th while ClojureScript is ranked 41st. The most important reason people chose Clojure is:
Clojure programmers are highly encouraged to use immutable data in their code. Therefore, most data will be immutable by default. State change is handled by functions (for transformations) and atoms (an abstraction that encapsulates the idea of some entity having an identity).
Specs
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Pros
Pro Immutability is the default
Clojure programmers are highly encouraged to use immutable data in their code. Therefore, most data will be immutable by default.
State change is handled by functions (for transformations) and atoms (an abstraction that encapsulates the idea of some entity having an identity).
Pro Minimal syntax
Being a LISP, programs are simple: they're just functions and data. That it doesn't get bogged down with syntax or the loftier FP concepts like monads makes it one of most approachable functional languages for beginners.
Pro Tries to solve problems as simply as possible
Simplicity is one of the pillars on which Clojure is built. Clojure tries to solve many problems in software development as simply as possible. Instead of building complex interfaces, objects or factories, it uses immutability and simple data structures.
Pro Good for writing concurrent programs
Since Clojure is designed for concurrency, it offers things like Software Transaction Memory, functional programming without side-effects and immutable data structures right out of the box. This means that the development team can focus their energies on developing features instead of concurrency details.
Pro Huge ecosystem of libraries to work with
There's a very large ecosystem of high-quality Clojure libraries which developers can use. One example is Incanter. It's a great data analytics library and a very powerful tool for dealing with matrices, datasets and csv files.
Pro Cross platform
Clojure compiles to JVM bytecode and runs inside the JVM. This means that applications written in Clojure are cross-platform out of the box.

Pro Rich Hickey
The creator is so awesome, he's a feature. Just look up his talks and see why.
Pro Dynamic language
A superb data processing language. While rich type and specification systems are available they are optional.
Pro Extensible
Clojure has an elegant macro system which enables language additions, Domain-specific languages (DSLs), to be created much easier than most other languages (with the exception of Racket, perhaps).
Pro Great tool used in automating, configuring and managing dependencies available
Leiningen is a very useful tool for Clojure developers. It helps wiht automation, configuration and dependency management. It's basically a must for every Clojure project.
Pro No C/Java syntax
Refreshing, BTW!

Pro Game is available with which you can learn Clojure
Nightmod is a tool used to make "live-moddable" games. It displays the game's code while you are playing and allows you to inject new code using Clojure. This can be a fun and useful experience for people trying to learn Clojure.
Pro Live interactive programming with figwheel
Figwheel builds your ClojureScript code and hot loads it into the browser as you are coding! Every time you save your ClojureScript source file, the changes are sent to the browser so that you can see the effects of modifying your code in real time.
Pro Simple syntax
Lispness makes ClojureScript trivial to comprehend after an initial learning overhead.
Pro Easy to use existing JavaScript libraries
Clojure and ClojureScript are designed to be able to interact with their host. So the language by design makes it is easy to use existing JS libraries.
Pro Targets Google Closure-ready JavaScript for immense optimizations
Google's Closure Library converts regular JavaScript into a highly optimized form - including dead code analysis/elimination. It can even remove pieces of unused code from 3rd party libraries (eg, if you import jQuery but only use one function, Google Closure includes only that piece).
Pro Share application logic between browser and Clojure server
Clojure is also able to run web servers, so one can reap similar benefits to NodeJS in terms of sharing code between client and server.

Pro Can be used with React out of the box
Pro Excellent build tools
Both Leiningen and Boot are great build tools that manage code dependencies and deployment.
Pro Excellent tools for web development
ClojureScript has superb wrappers around React.js (see Reagent) that make building single-page apps a breeze. With figwheel, it's a web dev experience unlike any other -- hotloaded code, repl interaction, and instantly reflected changes make good development fun and fast. You can add things like Garden to make CSS-writing part of the same holistic experience and suddenly all development is a pleasant, smooth process.
Pro The Spec core library
From the creator of Clojure:
Spec is a new core library (Clojure 1.9 and Clojurescript) to support data and function specifications in Clojure.
Writing a spec should enable automatic: Validation, Error reporting, Destructuring, Instrumentation, Test-data generation and Generative test generation.
Cons
Con Confusing error messages
Clojure's error messages more often than not are very confusing. They usually involve stack traces that do not thoroughly explain where the error was caused or what caused it.
Con Code tends to be nightmare to maintain for non-authors
Tendency to devolve into difficult to manage mess of styles. Not recommended for professional use.
Con Too cult-ish
Way too niche and in-group behavior, while trying to trash other languages. Only pays for select few, who run the "game" on others.
Con Tied to the JVM and it's limitations
Some language constructs were obviously created as workarounds for JVM limitations. This makes the language much less elegant than it could have been.
Also, the JVM has a very cumbersome FFI.
Con Syntax can be alien / jarring for those used to other Lisps
Perhaps some may consider this attribute an advantage, but I do not. Clojure does not attempt to maintain significant compatibility with other Lisps. So, if you already know a Lisp or are used to the way Lisp works in general, you'll probably be confused if you take a look at Clojure. See these resources for more details on this subject:
Con Tooling is horrible
I've never seen worse tooling before. Writing tests and getting test coverage reports is near impossible. Tooling is brittle and clunky. Feels prehistoric.
Con Syntax may seem cryptic to people not used to Lisp
Lisp is sometimes called "syntax-less" and this is bewildering to those steeped in Algol-type syntax (Java, Javascript, C, etc). Being a dialect of Lisp, ClojureScript's syntax may seem cryptic and hard to understand for people not used to it. While Lisp has very little syntax compared to other languages and it's generally considered pretty terse, there's still an initial overhead in learning the language.
