Clojure vs C#

Clojure programmers are highly encouraged to use immutable data in their code. Therefore, most data will be immutable by default.
State change is handled by functions (for transformations) and atoms (an abstraction that encapsulates the idea of some entity having an identity).

Being a LISP, programs are simple: they're just functions and data. That it doesn't get bogged down with syntax or the loftier FP concepts like monads makes it one of most approachable functional languages for beginners.

Simplicity is one of the pillars on which Clojure is built. Clojure tries to solve many problems in software development as simply as possible. Instead of building complex interfaces, objects or factories, it uses immutability and simple data structures.

Since Clojure is designed for concurrency, it offers things like Software Transaction Memory, functional programming without side-effects and immutable data structures right out of the box. This means that the development team can focus their energies on developing features instead of concurrency details.

There's a very large ecosystem of high-quality Clojure libraries which developers can use. One example is Incanter. It's a great data analytics library and a very powerful tool for dealing with matrices, datasets and csv files.

Clojure compiles to JVM bytecode and runs inside the JVM. This means that applications written in Clojure are cross-platform out of the box.

The creator is so awesome, he's a feature. Just look up his talks and see why.

A superb data processing language. While rich type and specification systems are available they are optional.

Clojure has an elegant macro system which enables language additions, Domain-specific languages (DSLs), to be created much easier than most other languages (with the exception of Racket, perhaps).

Leiningen is a very useful tool for Clojure developers. It helps wiht automation, configuration and dependency management. It's basically a must for every Clojure project.

Refreshing, BTW!

Nightmod is a tool used to make "live-moddable" games. It displays the game's code while you are playing and allows you to inject new code using Clojure. This can be a fun and useful experience for people trying to learn Clojure.

.NET offers rich functionality.

The Visual Studio IDE offers one of the best development environments. The Community Edition and Visual Studio Code can be used for free.

Can be designed visually with the Visual Studio designer for traditional Windows forms, WPF, or Web forms.

Lot's of tools and libraries available.

With Xamarin for Mobile (ios, android),
with .net core asp for server (linux, windows),
with .net core for desktop (windows, mac),
with mono for desktop (windows, linux),
with blazor for web client with webassembly.

However, it is not considered top for any of those categories, but it is top choice for Windows desktop with .net framework and top choice for Unity.

.net 5 will unify frameworks similar to JVM (just one).

Runs on Linux, Mac, and Windows.

Constant updates and bug fixes to many popular frameworks, as well as great first-party support from Microsoft. This can be a con as well in certain circumstances.

Being a C like language counts in favor for it as a general purpose programming language, given the ease of using existing skills to pick up this language easily.

There are other superior languages that could be used as a general purpose, such as: F#, Haskell, but the complexity of those languages, being functional, make them strange to the usual C Syntax.

C# is better than C whenever garbage collection, Objects, classes, data access, are needed. But C is going to be the choice when hardware access and performance are paramount.